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All SSRIsincluding fluvoxamineshould not be taken with any of the monoamine oxidase inhibitorMAOIclass of antidepressants such as isocarboxazidMarplanphenelzineNardiltranylcypromineParnateand procarbazineMatulaneother drugs that inhibit monoamine oxidase such as linezolidZyvoxand intravenous methylene blueSuch combinations may lead to confusionhigh blood pressuretremorand increased activityFluvoxamine should not be administered within 14 days of discontinuing an MAO inhibitorand MAO inhibitors should not be administered within 14 days of stopping fluvoxamineSimilar reactions occur if fluvoxamine is combined with other drugsfor exampletryptophanStJohn’s wortmeperidineDemeroland tramadolUltramthat increase serotonin in the brainFluvoxamine can inhibit the elimination of clozapineClozarilnecessitating dosage reductions of clozapineFluvoxamine also may inhibit the elimination and increase the blood levels of theophyllineTheodurUniphylalprazolamXanaxand triazolamHalcionleading to side effects from these drugsFluvoxamine may increase the effect of warfarinCoumadinJantovenleading to excessive bleedingWarfarin therapy should be monitored more frequently in patients who also are taking fluoxetineCombining SSRIs with aspirinnonsteroidal anti-inflammatory drugs or other drugs that affect bleeding may increase the likelihood of upper gastrointestinal bleedingFluvoxamine may increase blood levels of tizanidineZanaflexthioridazineMellarilalosetronLotronexand pimozideOrapleading to increased side effects of these drugs.

This medication may impair your thinking or reactionsAvoid driving or operating machinery until you know how fluvoxamine will affect you.

“I once had a horrible experience in my life losing a friend but then I got over it but met another friend BUT my mind was making me think I would lose my new friendlike my old friend who stopped being my friend without telling meAnyways I found out I had OCDI started luvoxIt did take a few extra weeks then expected but over the last month I’ve began to really not worryhave the compulsive consistent non stop worriesI’ve definitely came a long wayEspecially that my friend assured me if he would stop being my friend he would let me know”

Taking Luvox with other drugs that make you sleepy can worsen this effectAsk your doctor before taking a sleeping pillopioid medicationmuscle relaxeror medicine for anxietydepressionor seizures.

Get emergency medical help if you have any of these signs of an allergic reactionskin rash or hivesdifficulty order reminyl medication breathingswelling of your facelipstongueor throat.

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