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Theophylline has two distinct actions in the airways of patients with reversible obstructionsmooth muscle relaxationi.ebronchodilationand suppression of the response of the airways to stimulii.enon-bronchodilator prophylactic effectsWhile the mechanisms of action of theophylline are not known with certaintystudies in animals suggest that bronchodilatation is mediated by the inhibition of two isozymes of phosphodiesterasePDE III andto a lesser extentPDE IVwhile non-bronchodilator prophylactic actions are probably mediated through one or more different molecular mechanismsthat do not involve inhibition of PDE III or antagonism of adenosine receptorsSome of the adverse effects associated with theophylline appear to be mediated by inhibition of PDE IIIe.ghypotensiontachycardiaheadacheand emesisand adenosine receptor antagonisme.galterations in cerebral blood flow

All medicines may cause side effectsbut many people have noor minorside effectsCheck with your doctor if any of these most COMMON side effects persist or become bothersome:

Do not flush medications down the toilet or pour them into a drain unless instructed to do soProperly discard this product when it is expired or no longer neededConsult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Treatment of cardiac arrhythmias Sinus tachycardia and simple ventricular premature beats are not harbingers of life-threatening arrhythmiasthey do not require treatment in the absence of hemodynamic compromiseand they resolve with declining serum theophylline concentrationsOther arrhythmiasespecially those associated with hemodynamic compromiseshould be treated with antiarrhythmic therapy appropriate for the type of arrhythmia.

All medicines may cause side effectsbut many people have noor minorside effectsCheck with your doctor if any of these most COMMON side effects persist or become bothersome:

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