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Caduet is the brand name of a combination medicine that contains the drugs norvasc amlodipine and lipitor atorvastatin .
Information about Norvasc.
Tell your doctor if your condition does not improve or if it worsensfor exampleyour blood pressure readings remain high or increasechest pain continues or worsens
Elevated systolic or diastolic pressure causes increased cardiovascular riskand the absolute risk increase per mmHg is greater at higher blood pressuresso that even modest reductions of severe hypertension can provide substantial benefitRelative risk reduction from blood pressure reduction is similar across populations with varying absolute riskso the absolute benefit is greater in patients who are at higher risk independent of their hypertensionfor examplepatients with diabetes or hyperlipidemiaand such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal.
In rare caseswhen you first start taking Norvascyour angina may get worse or you could have a heart attackSeek emergency medical attention or call your doctor right away if you have symptoms such aschest pain or pressurepain spreading to your jaw or shouldernauseasweating.
Vasospastic AnginaNorvasc has been demonstrated to block constriction and restore blood flow in coronary arteries and arterioles in response to calciumpotassium epinephrineserotoninand thromboxane A2 analog in experimental animal models and in human coronary vessels in vitroThis inhibition of coronary spasm is responsible for the effectiveness of Norvasc in vasospasticPrinzmetal’s or variantangina.
CommentThe dosage should be adjusted according to patient responseIn generaltitration should proceed over 7 to 14 daysIf clinically warrantedtitration may proceed more rapidlyprovided the patient is assessed frequently.
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if someone taking norvasc has collapsed or is not breathing, call 911.